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@@ -1,11 +1,10 @@
-
-This is the readme for the model associated with the papers:
+# This is the readme for the model associated with the papers:
Ref: Laventovich and Hemkin, A mathematical model of spontaneous
-calcium(II) oscillations in astrocytes. J Theor Biol 2008;
+calcium(II) oscillations in astrocytes. *J Theor Biol* 2008;
251(4):553-60.
-Abstract:
+## Abstract:
Astrocytes exhibit oscillations and waves of Ca2+ ions within their
cytosol and it appears that this behavior helps facilitate the
@@ -21,23 +20,26 @@
mimicking experimental constraints we have found that this model
provides results that are qualitatively similar to experiment.
-To run the model:
+## To run the model:
Expand the archive and cd into the newly created directory and run:
-xppaut Ca-Oscil-Astrocyte.ode
+`xppaut Ca-Oscil-Astrocyte.ode`
then click on Initialcond -> Go
-
+
This simulation will make graphs similar to the paper of Laventovich
-and Hemkin. Note that the cytosolic calcium concentration shown in
+and Hemkin. Note that the cytosolic calcium concentration shown in
figure 3 of the paper should be increased by 10-fold.
-The model file was supplied by:
+## The model file was supplied by:
-Dr. Sheng-Nan Wu
-Cardiac Electrophysiology and Systems-biology Center (CESC)
-National Cheng Kung University Medical College
-Tainan 70101, Taiwan
+Dr. Sheng-Nan Wu
+Cardiac Electrophysiology and Systems-biology Center (CESC)
+National Cheng Kung University Medical College
+Tainan 70101, Taiwan
e-mail: snwu@mail.ncku.edu.tw
-
+
+---
+
+2025-06-02: Standardized to Markdown.